iga deficiencies การใช้

• Antibody deficiencies are also common, including common variable immunodeficiency and IgA deficiency.
• IgG class anti-DGP antibodies may be useful in people with IgA deficiency.
• As opposed to the related condition CVID, selective IgA deficiency is not associated with an increased risk of cancer.
• IgA deficiency occurs in 1 : 500 of the population, as is suggested by a pallor in the gamma zone.
• The most common such immunodeficiency is inherited selective IgA deficiency, occurring between 1 in 100 and 1 in 1000 persons, depending on population.
• Certain other immune deficiency states ( e . g . common variable immunodeficiency and IgA deficiency ) are also associated with increased risk of malignancy.
• Of note, selective IgA deficiency can complicate the diagnosis of one such condition, celiac disease, as the deficiency masks the high levels of certain IgA antibodies usually seen in celiac disease.
• Guidelines recommend that a total serum IgA level is checked in parallel, as people with coeliac with IgA deficiency may be unable to produce the antibodies on which these tests depend ( " false negative " ).